Immunohistochemistry Kits and Reagents
Abcam DAB Substrate Kit
DAB Substrate Kit
The product is subject to the following: Abcam Restricted Use Statement
Cole-Parmer COLE-PARMER 0.01 TO 100 MTORR
Cole-Parmer 0.01 To 100 mTorr Pressure/vacuum Pirani-Type Sensor, 3/4" Tube OD
Surmodics Inc 650 nm Liquid Stop Solution for TMB Microwell Substrates, 100mL
A liquid stop solution used in end point ELISA applications where a TMB substrate is used as the detection mechanism. Absorbance is read in the blue spectral range (650 nm).
Abcam TripleStain IHC Kit: M&R&G on human tissue (DAB, AP/Red & DAB/Ni), 6ML
Abcam's TripleStain IHC Kit (ab183291) is designed to be used with user-supplied goat, mouse and rabbit primary antibodies to detect three distinct antigens on a single human tissue or cell samples.
The product is subject to the following: Abcam Restricted Use Statement
ABclonal Technology Desmin Rabbit pAb
This gene encodes a muscle-specific class III intermediate filament. Homopolymers of this protein form a stable intracytoplasmic filamentous network connecting myofibrils to each other and to the plasma membrane. Mutations in this gene are associated with desmin-related myopathy, a familial cardiac and skeletal myopathy (CSM), and with distal myopathies.
Cayman Chemical p38 MAPK PhosphoThr180 Tyr18
Antigen: phosphopeptide corresponding to amino acid residues surrounding phospho-Thr180 and phospho-Tyr182 of rat p38 MAPK • Host: rabbit • Cross Reactivity: (+) human p38 MAPK • Application(s): WB • p38 MAPK is activated by both inflammatory cytokines and by stress. It is thought to be particularly important in diseases like asthma and autoimmunity but it also plays important roles in the stress response of the nervous system. Like the other MAPKs, p38 is activated by a dual specificity kinase that phosphorylates Thr180 and Tyr182.
Biotium Cytokeratin 8 (KRT8)(B22.1), Biotin conjugate, 0.1mg/mL
Cytokeratin 8 (CK8) belongs to the type II (or B or basic) subfamily of high molecular weight cytokeratins and exists in combination with cytokeratin 18 (CK18). CK8 is primarily found in the non-squamous epithelia and is present in majority of adenocarcinomas and ductal carcinomas. It is absent in squamous cell carcinomas. Hepatocellular carcinomas are defined by the use of antibodies that recognize only cytokeratin 8 and 18. CK8 exists on several types of normal and neoplastic epithelia, including many ductal and glandular epithelia such as colon, stomach, small intestine, trachea, and esophagus as well as in transitional epithelium. Anti-CK8 does not react with skeletal muscle or nerve cells. Epithelioid sarcoma, chordoma, and adamantinoma show strong positivity corresponding to that of simple epithelia (with antibodies against CK8, CK18 and CK19). Reportedly, anti-CK8 is useful for the differentiation of lobular ('ring-like, perinuclear') from ductal ('peripheral-predomina
ABclonal Technology Phospho-p38 MAPK-T180/Y182 Rabbit pAb
The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various environmental stresses and proinflammatory cytokines. The activation requires its phosphorylation by MAP kinase kinases (MKKs), or its autophosphorylation triggered by the interaction of MAP3K7IP1/TAB1 protein with this kinase. The substrates of this kinase include transcription regulator ATF2, MEF2C, and MAX, cell cycle regulator CDC25B, and tumor suppressor p53, which suggest the roles of this kinase in stress related transcription and cell cycle regulation, as well as in genotoxic stress response. Four alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
Biotium CD6(3F7B5), CF594 conjugate, 0.1mg/mL
CD6 is a type I transmembrane glycoprotein that contains a 24-amino acid signal sequence, three extracellular scavenger receptor cysteine-rich (SRCR) domains, a membrane-spanning domain and a 44-amino acid cytoplasmic domain. The CD6 glycoprotein is tyrosine phosphorylated during TCR-mediated T cell activation. CD6 shows significant homology to CD5. CD6 is present on mature thymocytes, peripheral T cells and a subset of B cells. Antibodies to CD6 are used to deplete T cells from bone marrow transplants to prevent graft versus host disease.Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
Enzo Life Sciences MULTIVIEW (mouse-HRP/rabbit-AP) IHC kit (1x100tests)
Superior multiplex IHC kit for efficient detection of multiple antigens in a single tissue sample. The MULTIVIEW (mouse-HRP/rabbit-AP) IHC kit is a non-biotin one-step detection system suitable for demonstrating antigens in formalin-fixed paraffin-embedded tissues and cryostat sections. The kit may also be used with blood smears, cytosmears, and cell preparations. Assay Time: ~2 hours. Applications: IHC. Contents: Peroxidase Block, POLYVIEW IHC reagent (mouse-HRP), POLYVIEW IHC reagent (rabbit-AP), HIGHDEF IHC chromogen substrate (DAB, stable) buffer & chromogen, HIGHDEF red IHC chromogen (AP) buffer & chromogen, Empty mixing bottles
Active Motif MAXwash™ Washing Medium
MAXwash Washing Medium is a proprietary formulation designed and optimized to eliminate non-specific primary and secondary antibody binding. It has been tested and proven effective at eliminating off-target antibody binding in immunofluorescence assays.
Biotium Napsin-A(NAPSA/1238), Biotin conjugate, 0.1mg/mL
Napsin is a pepsin-like aspartic proteinase connected with maturation of surfactant protein B. There are two closely related napsins, napsin A and napsin B. Napsin A is expressed as a single chain protein. Immunohistochemical studies revealed high expression levels of napsin A in human lung and kidney but low expression in spleen. Napsin A is expressed in type II pneumocytes and in adenocarcinomas of lung. The high specificity expression of napsin A in adenocarcinomas of lung is useful to distinguish primary lung adenocarcinomas from adenocarcinomas of other organs.Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
Abcam TripleStain IHC Kit: M&R&G on human tissue (DAB, AP/Red & DAB/Ni), 60ML
Abcam's TripleStain IHC Kit (ab183291) is designed to be used with user-supplied goat, mouse and rabbit primary antibodies to detect three distinct antigens on a single human tissue or cell samples.
The product is subject to the following: Abcam Restricted Use Statement
Biocare Medical, LLC Goat-on-Rodent HRP-Polymer, 6 ml
Goat-on-Rodent HRP-Polymer is for goat primary antibodies on mouse, rat or human tissues and labeled with horseradish peroxidase. Goat antibodies are advantageous as the detection has minimum cross reactivity to mouse, rat or human IgG.
Biotium pS2 / pNR-2 / TFF1 (Estrogen-Regulated Protein) (TFF1/2969R), CF740 conjugate, 0.1mg/mL
This antibody recognizes a polypeptide of 6.5 kDa, identified as pS2 estrogen-regulated protein. Its epitope is localized between aa57-84 of human pS2 protein. pS2 is a trefoil peptide. Trefoil peptides are protease resistant molecules secreted throughout the gut that play a role in mucosal healing. These peptides contain three intra-chain disulfide bonds, forming the trefoil motif, or P-domain. pS2 is known to form dimers and this dimerization is thought to play a role in its protective and healing properties. About 60% of breast carcinomas are positive for pS2. Staining is cytoplasmic, often with localization to the Golgi apparatus. pS2 is shown to be localized in normal stomach mucosa, gastric fluid, goblet cells in the colon and small intestine, and in ulcerations of the gastrointestinal tract. Several studies have shown that pS2 is primarily expressed in estrogen receptor-positive breast tumors and it may define a subset of estrogen-dependent tumors that displays an increased